英文名称 | Tamoxifen |
---|---|
中文名称 | 他莫昔芬 |
CAS号 | 10540-29-1 |
分子式 | C26H29NO |
分子量 | 371.51 |
外观 | White to off-white |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名称 | Tamoxifen |
---|---|
中文名称 | 他莫昔芬 |
CAS号 | 10540-29-1 |
分子式 | C26H29NO |
分子量 | 371.51 |
外观 | White to off-white |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Tamoxifen is an orally active, selective estrogen receptor modulator (SERM) which exhibits both estrogenic agonist and antagonist effects. It blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity.