Routes of drug administration
Route | Abbreviation | Description |
Intracerebroventricular | i.c.v. | Into the ventricles of the brain |
Intra-arterial | i.a. | Into the lumen of an artery |
Intracerebral | i.c. | Into the brain |
Intradermal | i.d. | Into the dermal layer of the skin |
Intramuscular | i.m. | Into a skeletal muscle |
Intragastric | i.g. | Into the stomach |
Intraperitoneal | i.p. | Into the peritoneum (body cavity) |
Intravenous | i.v. | Into a vein |
Oral | p.o. | By mouth |
Subcutaneous | s.c. | Under the skin |
quaque die (Latin) | q.d. | once a day |
bis in die (Latin) | b.i.d. | twice a day |
ter in die (Latin) | t.i.d. | three times a day |
Targets
Abbreviation | Description |
Abl | V-abl Abelson murine leukemia viral oncogene homolog 1 |
ALK | anaplastic lymphoma kinase |
ATM | Ataxia telangiectasia mutated |
B-Raf | B-Raf proto-oncogene serine/threonine-protein kinase (B-RAF), also known as V-raf murine sarcoma viral oncogene homolog B1 |
Bcl-2 | B-cell lymphoma 2 |
Bcr | breakpoint cluster region |
Caspases | cysteine-aspartic proteases or cysteine-dependent aspartate-directed proteases |
CCR5 | co-receptors chemokine receptor 5 |
CDK | Cyclin-dependent kinase |
CFTR potentiator | Cystic fibrosis transmembrane conductance regulator |
CTSK | Cathepsin K |
c-Kit | CD117 (cluster of differentiation 117), also called KIT or C-kit receptor |
c-Met | mesenchymal-epithelial transition |
DNA-PK | DNA-dependent protein kinase |
DPP-4 | Dipeptidyl peptidase-4 |
EGFR | Epidermal growth factor receptor |
Factor Xa | Stuart-Prower factor, an enzyme of the coagulation cascade |
FGFR | Fibroblast growth factor receptor |
FLT-3 | fms-like tyrosine kinase-3 |
FTS | Farnesyl thiosalicylic acid |
GSK-3 | Glycogen synthase kinase 3 |
HER2 | Human epidermal growth factor receptor 2 |
HDAC | Histone deacetylase |
HIF | Hypoxia-inducible factor |
HSP-70 | heat-shock protein-70 |
HSP-90 | heat-shock protein-90 |
IGF-1R | Insulin-like growth factor 1 receptor |
JAK | Janus kinase |
JNK | c-Jun N-terminal kinases |
Ksp | Kinesin spindle protein |
MAPK | Mitogen-activated Protein Kinase |
MEK | MAPK/ERK kinase |
mGluRs | metabotropic glutamate receptors |
mTOR | Mammalian target of rapamycin |
NF-kB | Nuclear factor-κB |
p38 MAPK | p38 Mitogen-activated Protein Kinase |
p53 | protein 53 or tumor protein 53 |
PARP | Poly (ADP-ribose) polymerase |
PDGFR | platelet-derived growth factor receptor |
PDK-1 | phosphoinositide-dependent kinase-1 |
Rho | ρ factor |
PI3K | Phosphatidylinositol 3-kinases |
PKC | protein kinase C |
PLK | Polo-like kinase |
Ras | renin-angiotensin system |
RNAP | RNA Polymerase or RNApol |
S1PR1 | Sphingosine-1-phosphate receptor (S1P1) also known as endothelial differentiation gene 1 (EDG1) |
sPLA2 | Secreted phospholipase A2 |
Src | Rous sarcoma oncogene cellular homolog |
Stat | Signal Transducers and Activator of Transcription |
Survivin | baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5 |
TGF | Transforming growth factor |
TNF | Tumor necrosis factor |
VEGFR | Vascular Endothelial Growth Factor Receptor |
Wnt | a portmanteau of int and Wg and stands for "Wingless-related integration site" |
