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(R)-6-(N-(2-氯-4-氟苯基)氨磺酰基)环己-1-烯羧酸乙酯;瑞沙托维

Resatorvid (Synonyms: TAK-242; CLI-095;(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate)

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产品编号：CL1002

CAS No.：243984-11-4

MDLNo：

分子式：C15H17ClFNO4S

分子量：361.82

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产品库存

3-5days

目录价格

￥898.00

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产品库存

3-5days

目录价格

￥1288.00

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基本信息

中文名称	(R)-6-(N-(2-氯-4-氟苯基)氨磺酰基)环己-1-烯羧酸乙酯;瑞沙托维
英文名称	Resatorvid (Synonyms: TAK-242; CLI-095;(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate)
CAS号	243984-11-4
分子式	C15H17ClFNO4S
分子量	361.82
外观	Off-white to yellow solid
储存条件	Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

安全信息

产品详情

Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.
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