中文名称 | Y-27632 |
---|---|
英文名称 | Y-27632 (free base) |
CAS号 | 146986-50-7 |
分子式 | C14H21N3O |
分子量 | 247.34 |
外观 | White to off-white powder |
储存条件 | -20°C, protect from light, stored under nitrogen |
Y-27632 is a potent and selective inhibitor of ROCK1 (p160ROCK) with IC50 of 140 nM in a cell-free assay, it exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.
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