盐酸多柔比星 | 盐酸阿霉素
Doxorubicin (Adriamycin) Hydrochloride (Synonyms: Doxorubicin (DOX) HCl; Hydroxydaunorubicin hydrochloride; ADR;NSC 123127;Hydroxydaunorubicin HCl )
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¥260.00
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¥750.00
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基本信息
中文名称盐酸多柔比星 | 盐酸阿霉素
英文名称 Doxorubicin (Adriamycin) Hydrochloride (Synonyms: Doxorubicin (DOX) HCl; Hydroxydaunorubicin hydrochloride; ADR;NSC 123127;Hydroxydaunorubicin HCl )
CAS号25316-40-9
分子式C27H29NO11.HCl
分子量 579.98
MDLMFCD00077757
外观Orange red powder
储存条件Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
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Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.
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