(E)-4-羟基他莫昔芬
(E)-4-Hydroxytamoxifen; (E)-Afimoxifene
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基本信息
中文名称(E)-4-羟基他莫昔芬
英文名称 (E)-4-Hydroxytamoxifen; (E)-Afimoxifene
CAS号174592-47-3
分子式C26H29NO2
分子量387.51
外观White to off-white powder
储存条件Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
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产品详情

Afimoxifene, E-isomer, also called (E)-4-Hydroxytamoxifen, is a SERM and active metabolite of tamoxifen. The E isomer is less active thatn the Z isomer. It induces autophagy, vacuole formation and KRAS degradation in cancerl cells and decreases contractility in myocytes.

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