中文名称 | (E/Z)-4-羟基他莫昔芬 | 阿非昔芬 |
---|---|
英文名称 | (E/Z)-4-Hydroxytamoxifen | Afimoxifene | cis/trans-4-Hydroxytamoxifen |
CAS号 | 68392-35-8 |
分子式 | C26H29NO2 |
分子量 | 387.51 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
4-Hydroxytamoxifen (Afimoxifene) is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. It activates on-target modification frequency for intein-Cas9 variants.
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