中文名称 | 7-表-10-脱乙酰基紫杉醇;10-去乙酰-7-差向紫杉醇 |
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英文名称 | 7-Epi-10-Deacetyl Paclitaxel |
CAS号 | 78432-77-6 |
分子式 | C45H49NO13 |
分子量 | 811.87 |
外观 | White to off-white powder |
10-deacetyl Paclitaxel (10-DAP) is a taxane and precursor in the semisynthetic synthesis of paclitaxel that has been found in Taxus and has anticancer activity. It is cytotoxic to KB carcinoma cells (EC50 = 0.027 μg/ml).10-DAP (16 mg/kg) reduces tumor growth in the PS mouse lymphocytic leukemia model.
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