中文名称 | 卡巴他赛 |
---|---|
英文名称 | Cabazitaxel (Synonyms: XRP6258; RPR-116258A;TXD 258;Taxoid XRP6258) |
CAS号 | 183133-96-2 |
分子式 | C45H57NO14 |
分子量 | 835.93 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Cabazitaxel is a semi-synthetic derivative of a natural taxoid that kills cancer cells by inhibiting cell division and growth. Cabazitaxel exerts its effects by inhibiting microtubule growth and assembly, processes that are essential for cells to divide. Cabazitaxel induces autophagy via the PI3K/Akt/mTOR pathway.
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