| 中文名称 | 盐酸美格鲁特 |
|---|---|
| 英文名称 | Miglustat Hydrochloride (N-Butyldeoxynojirimycin Hydrochloride; NB-DNJ hydrochloride; OGT918 hydrochloride) |
| CAS号 | 210110-90-0 |
| 分子式 | C10H21NO4.HCl |
| 分子量 | 255.74 |
| 外观 | White to light brown |
| 储存条件 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Miglustat, also known as OGT 918 and NB-DNJ, is a drug developed by Actelion and is used primarily to treat Type I Gaucher disease (GD1). Miglustat inhibits glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids (it forms glucosylceramide and accumulates within the macrophages).
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