中文名称 | N-(3-((R)-1-((R)-4-羟基-2-氧代-6-苯乙基-6-丙基-5,6-二氢-2H-吡喃-3-基)丙基)苯基)-5-(三氟甲基)吡啶-2-磺酰胺;替拉那韦 |
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英文名称 | Tipranavir | TPV | PNU-140690 |
CAS号 | 174484-41-4 |
分子式 | C31H33F3N2O5S |
分子量 | 602.66 |
MDL | MFCD00949098 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activity and dimerisation and has potent activity against multiple protease inhibitor (PI) HIV-1 isolates (IC50 of 66-410 nM). Tipranavir inhibits SARS-CoV-2 3CLpro activity.
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