中文名称 | (S)-N-((2S,4S,5S)-5-(2-(2,6-二甲基苯氧基)乙酰胺基)-4-羟基-1,6-二苯基己-2-基)-3-甲基-2-(2-氧代四氢嘧啶-1(2H)-基)丁酰胺; 洛匹那韦 |
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英文名称 | Lopinavir (Synonyms: ABT-378) |
CAS号 | 192725-17-0 |
分子式 | C37H48N4O5 |
分子量 | 628.80 |
MDL | MFCD22628840 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related drug ritonavir.
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