索拉非尼
Sorafenib; BAY 43-9006; Sorafenib Base; Sorafenib Free Base
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选择规格
500 mg 1 g
产品库存
In-stock
目录价格
¥478.00
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产品库存
In-stock
目录价格
¥768.00
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- +
基本信息
中文名称索拉非尼
英文名称 Sorafenib; BAY 43-9006; Sorafenib Base; Sorafenib Free Base
CAS号284461-73-0
分子式C21H16ClF3N4O3
分子量464.82
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
安全信息
产品详情

Sorafenib (BAY549085; BAY-549085; BAY439006; BAY-439006; Nexavar; SFN) an approved anticancer medication, is a potent and orally bioavailable multikinase inhibitor with potential anticancer activity (BAY549085; BAY-549085; BAY439006; BAY-439006; Nexavar; SFN). In enzymatic assays, it inhibits numerous kinases, including Raf-1, B-Raf, and VEGFR-2, with IC50 values of 6 nM, 22 nM, and 90 nM, respectively. The FDA granted sorafenib approval in 2005 to treat advanced renal cancer.

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索拉非尼