| 中文名称 | 戊司泊达 | 伐司扑达 |
|---|---|
| 英文名称 | Valspodar (Synonyms: PSC-833;PSC833;PSC 833;6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A) |
| CAS号 | 121584-18-7 |
| 分子式 | C63H111N11O12 |
| 分子量 | 1214.62 |
| 外观 | White to yellow powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Valspodar, also known as PSC-833, is an analogue of cyclosporin-A. Valspodar inhibits p-glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention and activity of some drugs in some drug-resistant tumor cells. This agent also induces caspase-mediated apoptosis.
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