2-(2,4-二氟苯基)-6-(1-(2,6-二氟苯基)脲基)烟酰胺
VX-702
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基本信息
中文名称2-(2,4-二氟苯基)-6-(1-(2,6-二氟苯基)脲基)烟酰胺
英文名称 VX-702
CAS号745833-23-2
分子式C19H12F4N4O2
分子量404.32
MDL MFCD11616590
外观White to off-white powder
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VX-702 is recognized as a highly selective inhibitor of p38α MAPK, with a 14-fold greater potency against p38α compared to p38β. This second-generation inhibitor is known for its high specificity and oral activity, making it a valuable tool in the research and potential treatment of inflammatory diseases, particularly rheumatoid arthritis.

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2-(2,4-二氟苯基)-6-(1-(2,6-二氟苯基)脲基)烟酰胺