| 中文名称 | 头孢妥仑匹酯 |
|---|---|
| 英文名称 | Cefditoren Pivoxil (Synonyms: Cefditoren pivoxyl; Cefditoren pivaloyloxymethyl ester; ME 1207; ME-1207) |
| CAS号 | 117467-28-4 |
| 分子式 | C25H28N6O7S3 |
| 分子量 | 620.72 |
| 外观 | Light yellow powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Cefditoren Pivoxil (ME-1207) is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria.
Cefditoren pivoxil is an orally bioavailable prodrug form of the broad-spectrum cephalosporin antibiotic cefditoren. Cefditoren pivoxil is hydrolyzed by intestinal wall esterases to form cefditoren. Cefditoren pivoxil is effective against systemic S. aureus, E. coli, K. pneumoniae, P. mirabilis, or S. marcescens infections in mice with ED50 values of 10, 2.5, 11, 4.4, and 11 mg/kg, respectively.Formulations containing cefditoren pivoxil were previously used in the treatment of acute bacterial exacerbations of chronic bronchitis and community-acquired pneumonia.
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