中文名称 | 芦比替定 | 卢比克替定 |
---|---|
英文名称 | Lurbinectedin | PM01183 | LY-01017 | Tryptamicidin |
CAS号 | 497871-47-3 |
分子式 | C41H44N4O10S |
分子量 | 784.87 |
MDL | MFCD22665743 |
外观 | White to light yellow powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively.
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