中文名称 | 阿齐瑞格 |
---|---|
英文名称 | Azeliragon (TTP488) |
CAS号 | 603148-36-3 |
分子式 | C32H38ClN3O2 |
分子量 | 532.13 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule that inhibits the receptor for advanced glycation endproducts (RAGE), which is an immunoglobulin-like cell surface receptor overexpressed in brain tissues of patients with AD.
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