(R)-(+)-反式-4-(1-氨基乙基)-N-(4-吡啶基)环己烷甲酰胺二盐酸盐单水合物/反-4-[(1R)-1-氨基乙基]-N-4-吡啶-环己甲酰胺盐酸盐一水合物
Y27632 HCl hydrate | (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate | Y-27632 Dihydrochloride Monohydrate
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中文名称(R)-(+)-反式-4-(1-氨基乙基)-N-(4-吡啶基)环己烷甲酰胺二盐酸盐单水合物/反-4-[(1R)-1-氨基乙基]-N-4-吡啶-环己甲酰胺盐酸盐一水合物
英文名称 Y27632 HCl hydrate | (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate | Y-27632 Dihydrochloride Monohydrate
CAS号331752-47-7
分子式C14H25Cl2N3O2
分子量338.27
外观White to off white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriuretic peptide production, cell size, protein synthesis, and myofibrillar organization. Y27632 prevents dimethylnitrosamine-induced hepatic fibrosis in rats, increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium, affects initial heart myofibrillogenesis in cultured chick blastoderm, promotes the proliferation and cell cycle progression of cultured astrocyte from spinal cord.

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Y-27632
trans-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐 | Y-27632 二盐酸盐 | (R)-(+)-反式-4-(1-氨基乙基)-N-(4-吡啶基)环己烷甲酰胺 二盐酸盐
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(R)-(+)-反式-4-(1-氨基乙基)-N-(4-吡啶基)环己烷甲酰胺二盐酸盐单水合物/反-4-[(1R)-1-氨基乙基]-N-4-吡啶-环己甲酰胺盐酸盐一水合物
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