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(S)-(3,4-二氟-2-((2-氟-4-碘苯基)氨基)苯基)(3-羟基-3-(哌啶-2-基)氮杂环丁烷-1-基)甲酮;考比替尼

(S)-(3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone; Cobimetinib (Synonyms: GDC-0973; XL518; RG7420)

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产品编号：CL1287

CAS No.：934660-93-2

MDLNo：MFCD22124461

分子式：C21H21F3IN3O2

分子量：531.31

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￥800.00

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基本信息

中文名称	(S)-(3,4-二氟-2-((2-氟-4-碘苯基)氨基)苯基)(3-羟基-3-(哌啶-2-基)氮杂环丁烷-1-基)甲酮;考比替尼
英文名称	(S)-(3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone; Cobimetinib (Synonyms: GDC-0973; XL518; RG7420)
CAS号	934660-93-2
分子式	C21H21F3IN3O2
分子量	531.31
MDL	MFCD22124461
外观	Off-white solid powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

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产品详情

Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, and showing no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.
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