阿贝西利 | 玻玛西尼
LY2835219 free base | Abemaciclib | LY2835219
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基本信息
中文名称阿贝西利 | 玻玛西尼
英文名称 LY2835219 free base | Abemaciclib | LY2835219
CAS号1231929-97-7
分子式C27H32F2N8
分子量506.59
外观Off-white to yellow powder
储存条件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Abemaciclib (formerly known as LY2835219) is a potent and selective, and orally bioavailable dual inhibitor of CDK4 (cyclin-dependent kinase) and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively.

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阿贝西利 | 玻玛西尼