中文名称 | 阿贝西利 | 玻玛西尼 |
---|---|
英文名称 | LY2835219 free base | Abemaciclib | LY2835219 |
CAS号 | 1231929-97-7 |
分子式 | C27H32F2N8 |
分子量 | 506.59 |
外观 | Off-white to yellow powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Abemaciclib (formerly known as LY2835219) is a potent and selective, and orally bioavailable dual inhibitor of CDK4 (cyclin-dependent kinase) and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively.
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