中文名称 | A-1155463 |
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英文名称 | A-1155463 |
CAS号 | 1235034-55-5 |
分子式 | C35H32FN5O4S2 |
分子量 | 669.79 |
外观 | Off-white to yellow powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM).
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