Pyridostatin (RR82)
Pyridostatin (Synonyms: RR82)
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中文名称Pyridostatin (RR82)
英文名称 Pyridostatin (Synonyms: RR82)
CAS号1085412-37-8
分子式C31H32N8O5
分子量596.64
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Pyridostatin (RR82) is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets the proto-oncogene Src. Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.
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