中文名称 | Pyridostatin (RR82) |
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英文名称 | Pyridostatin (Synonyms: RR82) |
CAS号 | 1085412-37-8 |
分子式 | C31H32N8O5 |
分子量 | 596.64 |
Pyridostatin (RR82) is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets the proto-oncogene Src. Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.
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