中文名称 | CEP-28122 mesylate salt |
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英文名称 | CEP-28122 mesylate salt (Synonyms:CEP-28122 (Mesylate salt)) |
CAS号 | 2070009-30-0 |
分子式 | C29H39ClN6O6S |
分子量 | 635.17 |
CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor, with an IC50 value of 1.9 nM for recombinant ALK kinase activity. CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity.
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