一甲基澳瑞他汀 E
Monomethyl auristatin E (Synonyms: MMAE; SGD-1010;Monomethylauristatin E)
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基本信息
中文名称一甲基澳瑞他汀 E
英文名称 Monomethyl auristatin E (Synonyms: MMAE; SGD-1010;Monomethylauristatin E)
CAS号474645-27-7
分子式C39H67N5O7
分子量717.98
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Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.

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一甲基澳瑞他汀 E