依克立达
Elacridar (Synonyms: GF120918; GW0918; GG918; GW120918)
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¥226.00
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基本信息
中文名称依克立达
英文名称 Elacridar (Synonyms: GF120918; GW0918; GG918; GW120918)
CAS号143664-11-3
分子式C34H33N3O5
分子量563.64
MDLMFCD00912604
外观Light yellow to brown powder
储存条件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
安全信息
产品详情

Elacridar is an orally active P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar can be used to examine the influence of efflux transporters on agent distribution to brain and the research of cancer.

GF120918 (Elacridar) is a very potent inhibitor of the ABC transporters MDR-1 (P-gp) and BCRP. GF120918 increases the bioavailability of cytotoxic anti-tumor drugs, and also leads to increased levels of anti-HIV drugs in the brain and CNS.

GF120918 (Elacridar) is an inhibitor of MDR-1 (P-gp).

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Elacridar | GF120918 |  GW0918 | GG918 | GW120918 ABC transporters MDR-1 (P-gp) inhibitor |  N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide

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