中文名称 | 阿齐沙坦酯钾盐 |
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英文名称 | Azilsartan Kamedoxomil; Azilsartan Medoxomil Monopotassium |
CAS号 | 863031-24-7 |
分子式 | C30H23KN4O8 |
分子量 | 606.62 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Azilsartan medoxomil is a prodrug, is hydrolyzed to azilsartan in the gastrointestinal tract during absorption. Azilsartan is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan blocks the vasoconstrictor and aldosteronesecreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is, therefore, independent of the pathway for angiotensin II synthesis.
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