中文名称 | Infigratinib | GJ-398 | NVP-BGJ398 |
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英文名称 | Infigratinib | GJ-398 | NVP-BGJ398 |
CAS号 | 872511-34-7 |
分子式 | C26H31Cl2N7O3 |
分子量 | 560.48 |
外观 | White to yellow powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
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