帕唑帕尼
Pazopanib (Synonyms: GW786034)
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基本信息
中文名称帕唑帕尼
英文名称 Pazopanib (Synonyms: GW786034)
CAS号444731-52-6
分子式C21H23N7O2S
分子量437.52
外观White powder
储存条件Store in a tightly closed container in a cool and dry place
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Pazopanib (GW-786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively.An oral angiogenesis inhibitor targeting VEGFR and PDGFR.A potent and selective inhibitor of tyrosine kinases, targeting VEGFR/c-KIT/PDGFR, blocking angiogenesis; as an oral antineoplastic agent.
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