依氟鸟氨酸盐酸盐一水合物
Eflornithine Hydrochloride Monohydrate
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500 mg 1 g 5 g
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¥388.00
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基本信息
中文名称依氟鸟氨酸盐酸盐一水合物
英文名称 Eflornithine Hydrochloride Monohydrate
CAS号96020-91-6
分子式C6H15ClF2N2O3
分子量236.64
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Eflornithine, also known as Difluoromethylornithine, is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells.

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