中文名称 | 塞拉菌素 | 司拉克丁 |
---|---|
英文名称 | Selamectin | Revolution | Stronghold | 165108-07-6 |
CAS号 | 220119-17-5 |
分子式 | C43H63NO11 |
分子量 | 769.96 |
外观 | White to off-white powder |
Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, Lymphatic filariae, and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC50 of 120 nM
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