中文名称 | 4-(2-氨乙基)苯磺酰氟盐酸盐 | AEBSF盐酸盐 |
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英文名称 | AEBSF HCl | AEBSF hydrochloride | 4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride | 4-(2-Aminoethyl)benzenesulfonyl Fluoride Hydrochloride |
CAS号 | 30827-99-7 |
分子式 | C8H11ClFNO2S |
分子量 | 239.69 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
AEBSF is a specific irreversible serine protease inhibitor. AEBSF inhibits the rat embryo implantation in vivo and interferes with cell adhesion in vitro. Both AEBSF and PMSF are sulfonyl fluorides and are sulfonylating agents. Sulfonyl fluorides act by reacting with the hydroxy group of the active site serine residue to form a sulfonyl enzyme derivative. This derivative may be stable for long periods of time except at high pH.
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