中文名称 | 西维来司钠四水合物 | 西维来司他钠 |
---|---|
英文名称 | Sivelestat Sodium Tetrahydrate | EI546 sodium tetrahydrate | LY544349 sodium tetrahydrate | ONO5046 sodium tetrahydrate |
CAS号 | 201677-61-4 |
分子式 | C20H29N2NaO11S |
分子量 | 528.51 |
外观 | White to off-white powder |
Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
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