依托考昔
Etoricoxib (Synonyms: MK-663; MK-0663; L-791456; Tauxib)
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产品库存
3-5days
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¥400.00
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产品库存
3-5days
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¥650.00
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产品库存
3-5days
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¥850.00
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基本信息
中文名称依托考昔
英文名称 Etoricoxib (Synonyms: MK-663; MK-0663; L-791456; Tauxib)
CAS号202409-33-4
分子式C18H15ClN2O2S
分子量358.84
外观Light yellow to yellow powder
储存条件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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产品详情

Etoricoxib (also known as MK-0663) is a non-steroidal anti-inflammatory drgu (NSAID) which acts as a selective and orally bioactive COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. Etoricoxib is a synthetic NSAID with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib binds specifically to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
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