中文名称 | 西他列汀磷酸盐一水合物 | 磷酸西他列汀一水合物 |
---|---|
英文名称 | Sitagliptin Phosphate Monohydrate |
CAS号 | 654671-77-9 |
分子式 | C16H20F6N5O6P |
分子量 | 523.32 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Sitagliptin phosphate (formerly also known as MK-431; trade name Januvia; Xelevia; Janumet) monohydrate, is an oral bioavailable, triazolopyrazine-based, potent inhibitor of DPP-IV (dipeptidyl peptidase-4) with an IC50 of 19 nM in Caco-2 cell extracts. It is an antihyperglycemic and antidiabetic medication.
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