替氟朵
Tifluadom | KC 5103 | dl-Tifluadom
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基本信息
中文名称替氟朵
英文名称 Tifluadom | KC 5103 | dl-Tifluadom
CAS号83386-35-0
分子式C22H20FN3OS
分子量393.48
储存条件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Tifluadom is a kappa-opioid receptor agonist. It has been shown to produce antinociception in the rotarod test and locomotor activity in mice, as well as having other pharmacological effects. Tifluadom is used to treat inflammatory disorders and autoimmune diseases. The mechanism of action of Tifluadom is not fully understood, but it may be due to its ability to bind with the benzodiazepine binding site on the GABAA receptor and also activate κ-opioid receptors. Tifluadom has been shown to increase the glomerular filtration rate (GFR) in rats by activating dopaminergic receptors that are involved in renal function.


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