中文名称 | SB 408124 |
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英文名称 | SB408124 |
CAS号 | 288150-92-5 |
分子式 | C19H18F2N4O |
分子量 | 356.37 |
外观 | White to off-white powder |
SB-408124 is a elective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). A critical role for the orexin-1 receptor (OX1R) in complex emotional behavior is emerging, such as overactivation of the OX1R pathway being associated with panic or anxiety states.
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