GSK-690693
GSK-690693 (Synonyms: GSK690693)
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基本信息
中文名称GSK-690693
英文名称 GSK-690693 (Synonyms: GSK690693)
CAS号937174-76-0
分子式C21H27N7O3
分子量425.48
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GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation.
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