| 中文名称 | GSK-690693 |
|---|---|
| 英文名称 | GSK-690693 (Synonyms: GSK690693) |
| CAS号 | 937174-76-0 |
| 分子式 | C21H27N7O3 |
| 分子量 | 425.48 |
GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation.
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