| 中文名称 | 替拉扎明 |
|---|---|
| 英文名称 | Tirapazamine (Synonyms: SR259075; SR4233; Win59075; SML 0552; SR 259075; Tirazone) |
| CAS号 | 27314-97-2 |
| 分子式 | C7H6N4O2 |
| 分子量 | 178.15 |
Tirapazamine (SR259075) is an anticancer agent that shows selective cytotoxicity for hypoxic cells in solid tumors, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death. Tirapazamine is an anticancer and bioreductive agent.Tirapazamine (SR259075) can enhance the cytotoxic effects of ionizing radiation in hypoxic cells.
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