中文名称 | CP-547632 TFA |
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英文名称 | CP-547632 TFA |
CAS号 | 2805804-54-8 |
分子式 | C20H24BrF2N5O3S·C2HF3O2 |
分子量 | 646.43 | 532.40(free) |
外观 | Off-white to light yellow powder |
储存条件 | 4°C, stored under nitrogen, away from moisture |
CP-547632 TFA is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC50s of 11 nM and 9 nM, respectively. CP-547632 TFA is selective for VEGFR2 and bFGF over EGFR, PDGFRβ, and related tyrosine kinases (TKs). CP-547632 TFA has antitumor efficacy.
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