两性霉素 B
Amphotericin B (Synonyms: NSC 527017;LNS-AmB)
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基本信息
中文名称两性霉素 B
英文名称 Amphotericin B (Synonyms: NSC 527017;LNS-AmB)
CAS号1397-89-3
分子式C47H73NO17
分子量924.09
外观Yellow powder
储存条件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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产品详情

Amphotericin B (AMB, NSC 527017) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes.

Amphotericin B binds ergosterol and induces membrane pore formations, increasing ROS and suppressing fungal growth. It also increases expression of IL-1-beta, TNF-alpha, BDNF and GDNF and protects against prion-induced neurodegeneration.
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