盐酸吉西他滨
Gemcitabine Hydrochloride (Synonyms: Gemcitabine HCl; LY 188011 hydrochloride;NSC 613327 HCl)
ChemLeader
产品编号:
CAS No.:
MDLNo:
分子式:
分子量:
选择规格
250 mg 500 mg 1 g 5 g
产品库存
In-stock
目录价格
¥100.00
会员价格
产品库存
In-stock
目录价格
¥150.00
会员价格
产品库存
In-stock
目录价格
¥250.00
会员价格
产品库存
In-stock
目录价格
¥400.00
会员价格
选择数量
- +
基本信息
中文名称盐酸吉西他滨
英文名称 Gemcitabine Hydrochloride (Synonyms: Gemcitabine HCl; LY 188011 hydrochloride;NSC 613327 HCl)
CAS号122111-03-9
分子式C₉H₁₂ClF₂N₃O₄
分子量299.66
外观White to off-white powder
储存条件 4°C, sealed storage, away from moisture and light
安全信息
产品详情

Gemcitabine is an active metabolite of the gemcitabine prodrugs NUC-1031   and gemcitabine elaidate   and a prodrug form of gemcitabine di- and triphosphates. Gemcitabine is phosphorylated by intracellular kinases to the intermediate metabolite gemcitabine monophosphate   and the active di- and triphosphate forms.It is cytotoxic to HepG2 hepatocellular carcinoma and A549 non-small cell lung cancer (NSCLC) cells (IC50s = 5.2 and 16 nM, respectively) and inhibits tumor growth in various breast, colon, lung, and pancreatic cancer mouse xenograft models. Gemcitabine (12 mg/kg) sensitizes tumors to antibodies targeting programmed cell death protein 1 (PD-1), decreases the number of tumor-infiltrating regulatory T cells (Tregs), and increases survival in an MC-38 syngeneic mouse model of colon carcinoma.  Formulations containing gemcitabine have been used in the treatment of cancer.
Tags: buy Gemcitabine HCl | Gemcitabine HCl supplier | purchase Gemcitabine HCl | Gemcitabine HCl cost | Gemcitabine HCl manufacturer | order Gemcitabine HCl | Gemcitabine HCl distributor

相关文献
相关产品
吉西他滨
浏览记录
盐酸吉西他滨
盐酸瑞伐拉赞(洛氟普啶)
3-((3R,4R)-4-甲基-3-(甲基(7H-吡咯并[2,3-d]嘧啶-4-基)氨基)哌啶-1-基)-3-氧代丙烷腈; 托法替尼; 托法替布
Adezmapimod Hydrochloride | SB 203580 Hydrochloride | RWJ 64809 Hydrochloride
恩斯特韦富马酸盐 | 恩赛特韦富马酸盐
Fmoc-苏氨酸磷酸苄酯
三(羟甲基)氨基甲烷 | 氨丁三醇 | 缓血酸胺
替加环素四甲磺酸盐
(S)-2-(叔丁基)哌嗪
反式-1-(4-羟基环己基)-4-(4-氟苯基)-5-(2-甲氧基嘧啶-4-基)咪唑