司他生坦钠 | 西他塞坦钠
Sitaxsentan sodium (Synonyms: IPI 1040 sodium; TBC11251 sodium)
ChemLeader
产品编号:
CAS No.:
MDLNo:
分子式:
分子量:
选择规格
选择数量
- +
基本信息
中文名称司他生坦钠 | 西他塞坦钠
英文名称 Sitaxsentan sodium (Synonyms: IPI 1040 sodium; TBC11251 sodium)
CAS号210421-74-2
分子式C18H14ClN2NaO6S2
分子量476.89
外观Light yellow to yellow powder
储存条件4°C, sealed storage, away from moisture
安全信息
产品详情

Sitaxsentan sodium (IPI 1040 sodium; TBC11251 sodium) is a potent, selective and orally activeendothelin A receptor (ETA) antagonist with an IC50 of 1.4 nM and a Ki of 0.43 nM. Sitaxsentan sodium exhibits an IC50 for the ETB receptor of as high as 9800 nM. Sitaxsentan sodium inhibits ET-1-induced phosphoinositide turnover. Sitaxsentan sodium can significantly alleviate pulmonary arterial hypertension (PAH) symptoms. Sitaxsentan sodium can be used for the study of PAH.

相关产品
司他生坦 | 塞塔生坦 | 西他生坦
浏览记录
司他生坦钠 | 西他塞坦钠
西维来司钠
细胞松驰素H;松胞菌素H
CX546
扎西他滨
松柏醇;(E)-4-(3-羟基丙-1-烯-1-基)-2-甲氧基苯酚