鲁比前列酮; 鲁比前列素;卢比前列腺素
Lubiprostone (Synonyms: RU-0211; SPI-0211)
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中文名称鲁比前列酮; 鲁比前列素;卢比前列腺素
英文名称 Lubiprostone (Synonyms: RU-0211; SPI-0211)
CAS号136790-76-6
分子式C20H32F2O5
分子量390.46
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Lubiprostone (SPI-0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research.
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