(1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-羟基-5,6-二甲基庚-3-烯-2-基)-7-甲基八氢-4H-茚-4-亚基)亚乙基)环己烷-1,3-二醇 ;帕立骨化醇
Paricalcitol
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中文名称(1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-羟基-5,6-二甲基庚-3-烯-2-基)-7-甲基八氢-4H-茚-4-亚基)亚乙基)环己烷-1,3-二醇 ;帕立骨化醇
英文名称 Paricalcitol
CAS号131918-61-1
分子式C27H44O3
分子量416.64
MDLMFCD08067734
外观White to off-white powder
储存条件4°C, protect from light, stored under nitrogen
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Paricalcitol, a selective VDR agonist, effectively suppresses PTH mRNA and inhibits parathyroid cell growth, treating secondary hyperparathyroidism in CKD. It's also associated with lower morbidity and improved survival rates compared to other VDRAs, with a favorable side-effect profile. Additionally, paricalcitol exhibits anti-inflammatory effects, potentially beneficial in managing CKD-related inflammation.
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(1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-羟基-5,6-二甲基庚-3-烯-2-基)-7-甲基八氢-4H-茚-4-亚基)亚乙基)环己烷-1,3-二醇 ;帕立骨化醇
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