培美曲赛二钠七水合物
Pemetrexed Disodium Heptahydrate | LY231514 disodium heptahydrate
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500 mg 1 g 5 g
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In-stock
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¥500.00
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In-stock
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¥800.00
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¥1280.00
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基本信息
中文名称培美曲赛二钠七水合物
英文名称 Pemetrexed Disodium Heptahydrate | LY231514 disodium heptahydrate
CAS号357166-29-1
分子式C20H33N5Na2O13
分子量597.48
外观White to off-white powder
储存条件4°C, sealed storage, away from moisture
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产品详情

Pemetrexed disodium heptahydrate (LY231514; HSDB7316; LY-231514; HSDB-7316; Alimta), the heptahydrated disodium salt of Pemetrexed and a pyrimidine-based antifolate, is an antifolate and antimetabolite anticancer medication. It targets TS, DHFR, and GARFT with Ki values of 1.3 nM, 7.2 nM, and 65 nM, in that order. In a variety of tumor types, including malignant mesothelioma, NSCLC (non-small cell lung carcinoma), carcinomas of the breast, colorectum, uterine cervix, head and neck, and bladder, pemetrexed shows strong antitumor activity.

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培美曲赛二钠七水合物