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扎西他滨

Zalcitabine (ddC; Dideoxycytidine; 2',3'-Dideoxycytidine)

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产品编号：CL2159

CAS No.：7481-89-2

MDLNo：

分子式：C9H13N3O3

分子量：211.22

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产品库存

In-stock

目录价格

￥600.00

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In-stock

目录价格

￥960.00

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产品库存

3-5days

目录价格

￥1536.00

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基本信息

中文名称	扎西他滨
英文名称	Zalcitabine (ddC; Dideoxycytidine; 2',3'-Dideoxycytidine)
CAS号	7481-89-2
分子式	C9H13N3O3
分子量	211.22
外观	White to light yellow powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

安全信息

产品详情

Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI). It is an antiviral pyrimidine nucleoside analogue effective against HIV replication. 2′,3′-Dideoxycytidine, when activated to its triphosphate, is incorporated into DNA by HIV-1 RT (HIV-1 reverse transcriptase), causing DNA chain termination and viral replication. Zalcitabine was the third antiretroviral to be approved by the Food and Drug Administration (FDA) for the treatment of HIV/AIDS. It is used as part of a combination regimen. Zalcitabine appears less potent than some other nucleoside RTIs, has an inconvenient three-times daily frequency and is associated with serious adverse events. For these reasons it is now rarely used to treat human immunodeficiency virus (HIV), and it has even been removed from pharmacies entirely in some countries.

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