中文名称 | 4-(2-(4-苄基哌啶-1-基)-1-羟丙基)苯酚 半((2R,3R)-2,3-二羟基丁二酸) |
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英文名称 | Ifenprodil hemitartrate | Ifenprodil tartrate | Ifenprodil (+)-tartrate salt | α-(4-Hydroxyphenyl)-β-methyl-4-benzyl-1-piperidineethanol (+)-tartrate salt|酒石酸艾芬地尔 | 艾芬地尔 (+)-酒石酸盐 | α-(4-羟基苯基)-β-甲基-4-苄基-1-哌啶乙醇 (+)-酒石酸盐 |
CAS号 | 23210-58-4 |
分子式 | C21H27NO2·1/2C4H6O6 |
分子量 | 400.49 | 325.45(free) |
MDL | MFCD01529999 |
外观 | White crystalline powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Ifenprodil is an inhibitor of the NMDA receptor, specifically of GluN1 (glycine-binding NMDA receptor subunit 1) and GluN2B (glutamate-binding NMDA receptor subunit 2) subunits. Additionally, ifenprodil inhibits GIRK channels, and interacts with alpha1 adrenergic, serotonin, and sigma receptors.
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