米托蒽醌二盐酸盐/盐酸米托蒽醌
Mitoxantrone Dihydrochloride; Mitoxantrone 2HCl
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¥260.00
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¥400.00
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¥860.00
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基本信息
中文名称米托蒽醌二盐酸盐/盐酸米托蒽醌
英文名称 Mitoxantrone Dihydrochloride; Mitoxantrone 2HCl
CAS号70476-82-3
分子式C22H29ClN4O6.2HCl
分子量517.4
外观Dark blue powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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 Mitoxantrone is an anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5.3 μM), thus inhibiting cell proliferation. It also inhibits HIV-1 integrase (IC50 = 3.8 μM). Mitoxantrone is exported from cells in an ATP- and glutathione-dependent manner by multidrug resistance protein-1.4 Formulations containing mitoxantrone have been used in the treatment of cancer and multiple sclerosis.

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米托蒽醌二盐酸盐/盐酸米托蒽醌