尼日利亚菌素钠盐
Nigericin Sodium Salt
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¥466.00
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基本信息
中文名称尼日利亚菌素钠盐
英文名称 Nigericin Sodium Salt
CAS号28643-80-3
分子式C40H67NaO11
分子量746.94
外观White to off-white powder
储存条件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Nigericin is a cationic ionophore that inhibits Golgi function and suppresses growth of gram positive bacteria. It also prevents viral activation and triggers activation of the NALP3 inflammasome. Nigericin acts as an H+, K+, Pb2+ ionophore. Most commonly it is an antiporter of H+ and K+. In the past nigericin was used as an antibiotic active against gram positive bacteria. It inhibits the Golgi functions in Eukaryotic cells. Its ability to induce K+ efflux also makes it a potent activator of the NLRP3 inflammasome.

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